Advances in glomerular filtration rate-estimating equations

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Estimating equations for glomerular filtration rate in children: laboratory considerations.

A recent report by Schwartz and coworkers has described improved equations for estimating glomerular filtration rate (GFR) in children (1 ). The equations were developed with data collected from 349 children 1–16 years of age with GFRs of approximately 20 –90 mL min 1 (1.73 m) 1 who were enrolled in the Chronic Kidney Disease in Children (CKiD) study. The new equations were developed to meet th...

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Validation of glomerular filtration rate-estimating equations in Chinese children

BACKGROUND Glomerular filtration rate (GFR) is essential for renal function evaluation and classification of chronic kidney disease (CKD), while the reference method in children are cumbersome. In the Chinese children, there was no data about GFR measured through plasma or renal clearance of the exogenous markers, and therefore no validated GFR-estimating tools in this population. METHODS We ...

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Using glomerular filtration rate estimating equations: clinical and laboratory considerations.

Glomerular filtration rate (GFR) estimating equations, infrequently used just a decade ago, are now recommended for the evaluation of kidney function for routine clinical care and are routinely reported by the vast majority of clinical laboratories (1 ). Current clinical guidelines recommend estimated GFR (eGFR) based on serum creatinine (eGFRCr) as the initial diagnostic test, and either a mea...

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Estimating Glomerular Filtration Rate in Older People

We aimed at reviewing age-related changes in kidney structure and function, methods for estimating kidney function, and impact of reduced kidney function on geriatric outcomes, as well as the reliability and applicability of equations for estimating glomerular filtration rate (eGFR) in older patients. CKD is associated with different comorbidities and adverse outcomes such as disability and pre...

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Comparisons between validated estimated glomerular filtration rate equations and isotopic glomerular filtration rate in HIV patients.

OBJECTIVE Understanding how best to measure renal function in HIV-infected patients is critical because estimated glomerular filtration rate (eGFR) in HIV-infected patients can be affected by ethnicity and body composition. We validated the available eGFR equations and compared them to the plasma Tc-diethylenetriaminepentaacetic acid (Tc-DTPA) clearance in HIV-infected patients. DESIGN Test o...

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ژورنال

عنوان ژورنال: Current Opinion in Nephrology and Hypertension

سال: 2010

ISSN: 1062-4821

DOI: 10.1097/mnh.0b013e32833893e2